Loliolide

• CAT Number: R061316
• CAS Number: 5989-02-6
• Molecular Formula: C11H16O3
• Molecular Weight: 196.24
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: (6S,7aR)-6-hydroxy-4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one
• InChI: InChI=1S/C11H16O3/c1-10(2)5-7(12)6-11(3)8(10)4-9(13)14-11/h4,7,12H,5-6H2,1-3H3/t7-,11+/m0/s1
• InChIKey: XEVQXKKKAVVSMW-WRWORJQWSA-N
• SMILES: CC1(CC(CC2(C1=CC(=O)O2)C)O)C

Loliolide (Cat.No:R061316) is a germination inhibitor that is isolated from Sargassum ringgoldianum subsp. coreanum. Loliolide exhibits antioxidant activity to protect the cells against H2O2-induced cell damage or apoptosis.

Reference

1.Grabarczyk, Małgorzata, et al. "Loliolide–the most ubiquitous lactone." Folia Biologica et Oecologica 11.1 (2015): 1-8.
2.Yang, Xiudong, et al. "Antioxidant activity and cell protective effect of loliolide isolated from Sargassum ringgoldianum subsp. coreanum." Algae 26.2 (2011): 201-208.
3.Park, Sang Hee, et al. "Loliolide presents antiapoptosis and antiscratching effects in human keratinocytes." International journal of molecular sciences 20.3 (2019): 651.