For research use only. Not for therapeutic Use.
LML134（Cat No.:I017831）is a selective antagonist of the orexin 1 receptor (OX1R), a G protein–coupled receptor involved in regulating arousal, stress response, and reward pathways. By blocking OX1R signaling, LML134 modulates neuronal activity linked to anxiety, addiction, and sleep–wake balance. This compound is a valuable pharmacological tool for investigating orexin biology and its role in neuropsychiatric and metabolic disorders. LML134 supports research into therapeutic strategies for conditions such as insomnia, substance abuse, and anxiety-related diseases, providing insight into the therapeutic potential of orexin receptor antagonism.
| CAS Number | 1542135-76-1 |
| Molecular Formula | C19H29N5O3 |
| Purity | ≥95% |
| IUPAC Name | [1-(1-methyl-6-oxopyridazin-3-yl)piperidin-4-yl] 4-cyclobutylpiperazine-1-carboxylate |
| InChI | InChI=1S/C19H29N5O3/c1-21-18(25)6-5-17(20-21)23-9-7-16(8-10-23)27-19(26)24-13-11-22(12-14-24)15-3-2-4-15/h5-6,15-16H,2-4,7-14H2,1H3 |
| InChIKey | BVUJMFFRMZRNAT-UHFFFAOYSA-N |
| SMILES | CN1C(=O)C=CC(=N1)N2CCC(CC2)OC(=O)N3CCN(CC3)C4CCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
