Lisavanbulin - CAS 1263384-43-5

Lisavanbulin, also known as BAL-101553, is an orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL-27862 with potential antitumor activity. Upon administration of BAL101553 and conversion into the active form BAL-27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells.

Catalog Number: I000866

CAS Number: 1263384-43-5

Molecular Formula: C26H29N9O3

Molecular Weight:515.6

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C26H29N9O3
Molecular Weight515.6
Target:microtublin inhibitor
Purity≥95%
Related CAS.1387574-54-0 (HCl)

Computed Descriptor

IUPAC Name(2S)-2,6-diamino-N-[4-[2-[2-[4-(2-cyanoethylamino)-1,2,5-oxadiazol-3-yl]benzimidazol-1-yl]acetyl]phenyl]hexanamide
InChIInChI=1S/C26H29N9O3/c27-13-4-3-6-19(29)26(37)31-18-11-9-17(10-12-18)22(36)16-35-21-8-2-1-7-20(21)32-25(35)23-24(34-38-33-23)30-15-5-14-28/h1-2,7-12,19H,3-6,13,15-16,27,29H2,(H,30,34)(H,31,37)/t19-/m0/s1
InChIKeyNIPZLALJRAHABJ-IBGZPJMESA-N
SMILESC1=CC=C2C(=C1)N=C(N2CC(=O)C3=CC=C(C=C3)NC(=O)C(CCCCN)N)C4=NON=C4NCCC#N