Lipoic acid - CAS 1200-22-2

Lipoic acid inhibits activation of nuclear factor kappa-B, which is involved in AIDS progression.
Target: NF-κB [1]
Lipoic acid is a powerful antioxidant, in organs of rats submitted to sepsis. Lipoic acid is effective in reducing MPO activity, lipid peroxidation in the liver, and protein carbonylation only in the kidney. Alpha-lipoic acid is a phase 2-inductive nutraceutical, a naturally occurring dithiol compound that functions as an essential cofactor for mitochondrial bioenergetic enzyme. Lipoic acid is recognized as a universal antioxidant capable of scavenging free radicals, chelating metals, regenerating endogenous antioxidants, and modulating various signal transduction pathways. [2] Lipoic acid suppresses HIV replication in cultured cells and enhanced helper T cells in mice. ALA inhibits replication of HIV by reducing the activity of reverse transcriptase, the enzyme responsible for manufacturing the virus from the DNA of lymphocytes.

Catalog Number: I000737

CAS Number: 1200-22-2

PubChem Substance ID:355038000

Molecular Formula: C8H14O2S2

Molecular Weight:206.33

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Molecular Formula: C8H14O2S2
Molecular Weight206.33
Target:NF-κB [1]
Solubility10 mM in DMSO