Linoleic Acid

• CAT Number: R023522
• CAS Number: 60-33-3
• Molecular Formula: C18H32O2
• Molecular Weight: 280.50
• Purity: ≥95%
• Synonyms: (9Z,12Z)-9,12-Octadecadienoic Acid ;?(Z,Z)-;9,12-Octadecadienoic Acid; (9Z,12Z)-9,12-Octadecadienoic Acid; (Z,Z)-9,12-Octadecadienoic Acid; (Z,Z)-9,12-Octadecadienoic Acid; 9-cis,12-cis-Linoleic Acid; 9Z,12Z-Linoleic Acid; 9Z,12Z-Octadecadienoic Acid
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: (9Z,12Z)-octadeca-9,12-dienoic acid
• InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
• InChIKey: OYHQOLUKZRVURQ-HZJYTTRNSA-N
• SMILES: CCCCCC=CCC=CCCCCCCCC(=O)O

Linoleic acid (Cat No.: R023522) is a polyunsaturated omega-6 fatty acid with the chemical formula C₁₈H₃₂O₂. It contains two cis double bonds at the 9th and 12th carbon positions and is essential for human health, as it cannot be synthesized by the body. Linoleic acid plays a crucial role in maintaining cell membrane integrity, supporting skin health, and regulating inflammatory responses. It is commonly found in vegetable oils such as sunflower, safflower, and soybean oil and is used in dietary supplements and skincare products.

Reference

1. L. Chuang et al. “Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase” Lipids, Vol. 36(10),pp. 1099-1103, 2001
2. M. Wadman et al. “Conversion of linoleic acid into novel oxylipins by the mushroom Agaricus bisporus” Lipids, Vol. 40(11) pp. 1163-1170, 2005
3. P. Elias, B. Brown, V. Ziboh “The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in BarrierFunction” Journal of Investigative Dermatology, Vol.74 pp. 230–233, 1980