Linderane

• CAT Number: M056118
• CAS Number: 13476-25-0
• Molecular Formula: C15H16O4
• Molecular Weight: 260.29
• Purity: ≥95%
• Synonyms: (4E,12S,13R)-5,10-dimethyl-8,14,16-trioxatetracyclo[10.2.2.01,13.07,11]hexadeca-4,7(11),9-trien-15-one
• InChI: InChI=1S/C15H16O4/c1-8-4-3-5-15-13(19-15)12(18-14(15)16)11-9(2)7-17-10(11)6-8/h4,7,12-13H,3,5-6H2,1-2H3/b8-4+/t12-,13+,15?/m0/s1
• InChIKey: KBMSVODXFLAQNJ-WDIVDLRRSA-N
• SMILES: CC1=CCCC23C(O2)C(C4=C(C1)OC=C4C)OC3=O

Linderane (Cat No.: M056118) is a naturally occurring sesquiterpene lactone isolated from plants of the Lindera genus, commonly used in traditional Chinese medicine. It features a complex tricyclic structure with an epoxide and lactone moiety, contributing to its notable biological activities. Linderane exhibits anti-inflammatory, hepatoprotective, and antioxidant properties, making it a subject of interest in pharmacological research. Its potential therapeutic effects are linked to modulation of oxidative stress and inflammatory signaling pathways, positioning it as a promising candidate in natural product-based drug discovery.

Reference

[1]. Wang H, et al. Mechanism-based inactivation of CYP2C9 by linderane. Xenobiotica. 2015;45(12):1037-46.
[Content Brief]