For research use only. Not for therapeutic Use.
Liarozole dihydrochloride（Cat No.:I046131）is an imidazole derivative that functions as a retinoic acid metabolism blocking agent (RAMBA). By inhibiting cytochrome P450-dependent enzymes responsible for retinoic acid degradation, it elevates endogenous retinoic acid levels, thereby enhancing retinoid signaling. Liarozole dihydrochloride has been studied in cancer research, particularly prostate and breast cancer, as well as in dermatological conditions like psoriasis and ichthyosis. Its ability to modulate retinoid pathways without direct retinoid administration makes it a valuable tool for exploring therapeutic strategies in oncology and skin disease research.
| CAS Number | 1883548-96-6 |
| Synonyms | 6-[(3-chlorophenyl)-imidazol-1-ylmethyl]-1H-benzimidazole;dihydrochloride |
| Molecular Formula | C17H15Cl3N4 |
| Purity | ≥95% |
| IUPAC Name | 6-[(3-chlorophenyl)-imidazol-1-ylmethyl]-1H-benzimidazole;dihydrochloride |
| InChI | InChI=1S/C17H13ClN4.2ClH/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15;;/h1-11,17H,(H,20,21);2*1H |
| InChIKey | NKDMRTVUEJWCCQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)Cl)C(C2=CC3=C(C=C2)N=CN3)N4C=CN=C4.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
