Leukotriene B4

• CAT Number: I010536
• CAS Number: 71160-24-2
• Molecular Formula: C20H32O4
• Molecular Weight: 336.47
• Purity: ≥95%
• Synonyms: Alternative Names: LTB4, 5,12-DiHETE
• Target: Leukotriene Receptor
• Solubility: Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50�g/ml)
• Storage: Store at -20C
• IUPAC Name: (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
• InChI: InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
• InChIKey: VNYSSYRCGWBHLG-AMOLWHMGSA-N
• SMILES: CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O

Leukotriene B4 (Cat No.: I010536) is a potent pro-inflammatory lipid mediator derived from arachidonic acid through the 5-lipoxygenase pathway. It plays a critical role in the immune response by promoting chemotaxis, activation, and adhesion of neutrophils to sites of inflammation. LTB4 contributes to the pathogenesis of various inflammatory diseases, including asthma, arthritis, and inflammatory bowel disease. It exerts its effects primarily through BLT1 and BLT2 receptors. Targeting LTB4 signaling is an area of interest for developing anti-inflammatory and immunomodulatory therapies.