For research use only. Not for therapeutic Use.
Lercanidipine-d3 hydrochloride（Cat No.:R008482）is a deuterium-labeled calcium channel blocker used in pharmacokinetic and bioavailability research. It is a stable isotope variant of lercanidipine, featuring three deuterium atoms that help distinguish it in mass spectrometry studies. As an L-type calcium channel antagonist, it reduces vascular resistance and is commonly studied for hypertension-related mechanisms. The hydrochloride form enhances its solubility for in vitro and in vivo applications. It is not intended for therapeutic use but is essential in drug metabolism and bioanalytical research to track drug behavior and improve precision dosing.
| CAS Number | 1189954-18-4 |
| Synonyms | 5-O-[1-[3,3-diphenylpropyl(trideuteriomethyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride |
| Molecular Formula | C36H39D3ClN3O6 |
| Purity | ≥95% |
| IUPAC Name | 5-O-[1-[3,3-diphenylpropyl(trideuteriomethyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride |
| InChI | InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H/i5D3; |
| InChIKey | WMFYOYKPJLRMJI-OWKBQAHQSA-N |
| SMILES | [2H]C([2H])([2H])N(CCC(C1=CC=CC=C1)C2=CC=CC=C2)CC(C)(C)OC(=O)C3=C(NC(=C(C3C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC)C)C.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
