LDV

• CAT Number: I015126
• CAS Number: 1155866-55-9
• Molecular Formula: C48H70N10O12
• Molecular Weight: 979.13
• Purity: ≥95%
• Synonyms: (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-4-methyl-2-[[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]propanoyl]amino]hexanoic acid
• InChI: InChI=1S/C48H70N10O12/c1-26(2)23-35(53-38(59)24-31-17-19-32(20-18-31)52-48(70)56-33-14-9-8-13-28(33)5)43(64)55-36(25-39(60)61)44(65)57-40(27(3)4)46(67)58-22-12-16-37(58)45(66)51-29(6)41(62)50-30(7)42(63)54-34(47(68)69)15-10-11-21-49/h8-9,13-14,17-20,26-27,29-30,34-37,40H,10-12,15-16,21-25,49H2,1-7H3,(H,50,62)(H,51,66)(H,53,59)(H,54,63)(H,55,64)(H,57,65)(H,60,61)(H,68,69)(H2,52,56,70)/t29-,30-,34-,35-,36-,37-,40-/m0/s1
• InChIKey: FQYZPSNPTJYQKB-CGTMUHGOSA-N
• SMILES: CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N3CCC[C@H]3C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

LDV (Cat No.:I015126) is a short tripeptide sequence that functions as a recognition motif for integrins, particularly the α4β1 (VLA-4) integrin. By mimicking natural extracellular matrix ligands, LDV competitively inhibits integrin-mediated cell adhesion and migration. Researchers use LDV to study cell–matrix interactions, leukocyte trafficking, and integrin signaling pathways. It is valuable in inflammation and immunology research, as well as in cancer metastasis studies where integrin activity plays a key role. LDV serves as a molecular tool for dissecting adhesion biology and therapeutic targeting strategies.