For research use only. Not for therapeutic Use.
LDN-209929 dihydrochloride（Cat No.:I015388）is a potent and selective antagonist of the metabotropic glutamate receptor 1 (mGluR1), a receptor implicated in excitatory neurotransmission and synaptic plasticity. By inhibiting mGluR1 signaling, it reduces excessive glutamatergic activity associated with neurological and psychiatric disorders. This compound is particularly valuable in research on pain modulation, neurodegeneration, and conditions such as anxiety, depression, and schizophrenia. Supplied as a dihydrochloride salt for enhanced solubility and handling, LDN-209929 is a useful tool for probing mGluR1-dependent pathways and advancing therapeutic discovery in neuroscience research.
| CAS Number | 1784281-97-5 |
| Synonyms | 3-(2-chloro-7-methoxyacridin-9-yl)sulfanylpropan-1-amine;dihydrochloride |
| Molecular Formula | C17H19Cl3N2OS |
| Purity | ≥95% |
| IUPAC Name | 3-(2-chloro-7-methoxyacridin-9-yl)sulfanylpropan-1-amine;dihydrochloride |
| InChI | InChI=1S/C17H17ClN2OS.2ClH/c1-21-12-4-6-16-14(10-12)17(22-8-2-7-19)13-9-11(18)3-5-15(13)20-16;;/h3-6,9-10H,2,7-8,19H2,1H3;2*1H |
| InChIKey | WOCCOXNODBCCGK-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)Cl.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
