For research use only. Not for therapeutic Use.
LDHA-IN-3（Cat No.:I044420）is a potent and selective inhibitor of lactate dehydrogenase A (LDHA), an enzyme critical for anaerobic glycolysis that catalyzes the conversion of pyruvate to lactate. By blocking LDHA activity, LDHA-IN-3 disrupts lactate production, thereby impairing energy metabolism in glycolysis-dependent cancer cells. This inhibition leads to reduced tumor growth and promotes oxidative stress and apoptosis. LDHA-IN-3 is a valuable tool in cancer metabolism research, particularly in exploring the Warburg effect and metabolic vulnerabilities in tumors. It supports therapeutic development targeting altered metabolic pathways in cancer and other proliferative diseases.
| CAS Number | 227010-33-5 |
| Synonyms | 1-phenylselanyl-4-(trifluoromethyl)benzene |
| Molecular Formula | C13H9F3Se |
| Purity | ≥95% |
| IUPAC Name | 1-phenylselanyl-4-(trifluoromethyl)benzene |
| InChI | InChI=1S/C13H9F3Se/c14-13(15,16)10-6-8-12(9-7-10)17-11-4-2-1-3-5-11/h1-9H |
| InChIKey | WJNWVLLRQJFFTC-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)[Se]C2=CC=C(C=C2)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
