LCKLSL hydrochloride

• CAT Number: I045820
• Molecular Formula: C30H58ClN7O8S
• Molecular Weight: 712.34
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoic acid;hydrochloride
• InChI: InChI=1S/C30H57N7O8S.ClH/c1-16(2)11-19(32)25(39)37-24(15-46)29(43)33-20(9-7-8-10-31)26(40)34-21(12-17(3)4)27(41)36-23(14-38)28(42)35-22(30(44)45)13-18(5)6;/h16-24,38,46H,7-15,31-32H2,1-6H3,(H,33,43)(H,34,40)(H,35,42)(H,36,41)(H,37,39)(H,44,45);1H/t19-,20-,21-,22-,23-,24-;/m0./s1
• InChIKey: AMMXZXCYTNGHOZ-HXDXACSPSA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)O)N.Cl

LCKLSL hydrochloride（Cat No.:I045820）is a synthetic hexapeptide (Leu-Cys-Lys-Leu-Ser-Leu) formulated as the hydrochloride salt to enhance solubility and stability. It functions as an inhibitor of thrombospondin-1 (TSP-1) binding to CD36, a key interaction involved in anti-angiogenic signaling. By disrupting this pathway, LCKLSL promotes angiogenesis and vascularization, making it a valuable research tool in studies of tissue repair, wound healing, and ischemic disease models. Its defined sequence and activity allow precise investigation of angiogenic mechanisms and therapeutic strategies aimed at enhancing blood vessel growth in regenerative medicine applications.