Lawesson’s Reagent

• CAT Number: R041992
• CAS Number: 19172-47-5
• Molecular Formula: C14H14O2P2S4
• Molecular Weight: 404.45
• Purity: ≥95%
• Synonyms: 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-Disulfide; 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide; 2,4-Bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide; 2,4-Bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4
• Storage: -20°C
• IUPAC Name: 2,4-bis(4-methoxyphenyl)-2,4-bis(sulfanylidene)-1,3,2lambda5,4lambda5-dithiadiphosphetane
• InChI: InChI=1S/C14H14O2P2S4/c1-15-11-3-7-13(8-4-11)17(19)21-18(20,22-17)14-9-5-12(16-2)6-10-14/h3-10H,1-2H3
• InChIKey: CFHGBZLNZZVTAY-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)P2(=S)SP(=S)(S2)C3=CC=C(C=C3)OC

Lawesson’s Reagent（Cat No.:R041992）is a sulfur-containing compound widely used in organic synthesis to convert carbonyl groups, such as ketones and esters, into their corresponding thiocarbonyl derivatives. Its structure features two phosphorus atoms each bonded to two aromatic rings and bridged by sulfur atoms. Typically a yellow crystalline solid, Lawesson’s Reagent is particularly effective in thionation reactions under mild conditions. It is valuable in synthesizing thioamides, thioketones, and thiolactones, and is favored for its selectivity and compatibility with a wide range of functional groups, making it essential in pharmaceutical and heterocyclic chemistry.