Lauryl maltose neopentyl glycol

• CAT Number: R061382
• CAS Number: 1257852-96-2
• Molecular Formula: C47H88O22
• Molecular Weight: 1005.19
• Purity: ≥95%
• Synonyms: (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[2-decyl-2-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]dodecoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C47H88O22/c1-3-5-7-9-11-13-15-17-19-47(20-18-16-14-12-10-8-6-4-2,25-62-43-39(60)35(56)41(29(23-50)66-43)68-45-37(58)33(54)31(52)27(21-48)64-45)26-63-44-40(61)36(57)42(30(24-51)67-44)69-46-38(59)34(55)32(53)28(22-49)65-46/h27-46,48-61H,3-26H2,1-2H3/t27-,28-,29-,30-,31-,32-,33+,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-/m1/s1
• InChIKey: MADJBYLAYPCCOO-VWHTXWAPSA-N
• SMILES: CCCCCCCCCCC(CCCCCCCCCC)(CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

Lauryl Maltose Neopentyl Glycol (Cat No.:R061382) is a mild, non-ionic detergent widely used for solubilizing and stabilizing membrane proteins, especially in structural biology. It consists of a neopentyl glycol core linked to two lauryl (C12) alkyl chains and two maltose sugar units, offering strong amphiphilicity and low critical micelle concentration (~0.01 mM). LMNG preserves protein functionality and native conformation, making it ideal for cryo-EM, crystallography, and biochemical assays. With high water solubility and minimal protein denaturation, LMNG is favored for isolating G protein–coupled receptors (GPCRs), ion channels, and respiratory complexes.