Laricitrin

• CAT Number: M016136
• CAS Number: 53472-37-0
• Molecular Formula: C16H12O8
• Molecular Weight: 332.264
• Purity: ≥95%
• Storage: Store at 4°C
• IUPAC Name: 2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxychromen-4-one
• InChI: InChI=1S/C16H12O8/c1-23-11-3-6(2-9(19)13(11)20)16-15(22)14(21)12-8(18)4-7(17)5-10(12)24-16/h2-5,17-20,22H,1H3
• InChIKey: CFYMYCCYMJIYAB-UHFFFAOYSA-N
• SMILES: COC1=CC(=CC(=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

Laricitrin is an O-methylated flavonol, a type of flavonoid. It is found in red grape (absent in white grape) and in Vaccinium uliginosum (bog billberries). It is one of the phenolic compounds present in wine.

Reference

1: Chang WA, Hung JY, Jian SF, Lin YS, Wu CY, Hsu YL, Kuo PL. Laricitrin
ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal
transducer and activator of transcription 3. Oncotarget. 2016 Dec
20;7(51):85220-85234. doi: 10.18632/oncotarget.13240. PubMed PMID: 27833081;
PubMed Central PMCID: PMC5356731.

2: Chang WA, Hung JY, Tsai YM, Hsu YL, Chiang HH, Chou SH, Huang MS, Kuo PL.
Laricitrin suppresses increased benzo(a)pyrene-induced lung tumor-associated
monocyte-derived dendritic cell cancer progression. Oncol Lett. 2016
Mar;11(3):1783-1790. Epub 2016 Jan 26. PubMed PMID: 26998077; PubMed Central
PMCID: PMC4774572.