Laricitrin

• CAT Number: M016136
• CAS Number: 53472-37-0
• Molecular Formula: C16H12O8
• Molecular Weight: 332.26
• Purity: ≥95%
• Synonyms: Laricitrin;LARICITRIN(SH)
• Storage: Store at 4°C
• IUPAC Name: 2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxychromen-4-one
• InChI: InChI=1S/C16H12O8/c1-23-11-3-6(2-9(19)13(11)20)16-15(22)14(21)12-8(18)4-7(17)5-10(12)24-16/h2-5,17-20,22H,1H3
• InChIKey: CFYMYCCYMJIYAB-UHFFFAOYSA-N
• SMILES: COC1=CC(=CC(=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

Laricitrin (Cat No.: M016136) is a naturally occurring flavonol, part of the larger flavonoid family found in plants. It is primarily present in red grapes, blueberries, and certain types of wine. Known for its antioxidant and anti-inflammatory properties, laricitrin contributes to cellular protection against oxidative stress. It also exhibits potential in cardiovascular health and cancer prevention by modulating signaling pathways. As a dietary polyphenol, laricitrin is being explored for its pharmacological applications in nutraceuticals and therapeutic research, particularly in chronic disease management.

Reference

1: Chang WA, Hung JY, Jian SF, Lin YS, Wu CY, Hsu YL, Kuo PL. Laricitrin
ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal
transducer and activator of transcription 3. Oncotarget. 2016 Dec
20;7(51):85220-85234. doi: 10.18632/oncotarget.13240. PubMed PMID: 27833081;
PubMed Central PMCID: PMC5356731.

2: Chang WA, Hung JY, Tsai YM, Hsu YL, Chiang HH, Chou SH, Huang MS, Kuo PL.
Laricitrin suppresses increased benzo(a)pyrene-induced lung tumor-associated
monocyte-derived dendritic cell cancer progression. Oncol Lett. 2016
Mar;11(3):1783-1790. Epub 2016 Jan 26. PubMed PMID: 26998077; PubMed Central
PMCID: PMC4774572.