Lamotrigine

• CAT Number: A000796
• CAS Number: 84057-84-1
• Molecular Formula: C₉H₇Cl₂N₅
• Molecular Weight: 256.09
• Purity: ≥95%
• Synonyms: 84057-84-1; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; Lamictal; Lamictal Cd; Lamotrigina
• Target: Sodium Channel
• Solubility: >12.3mg/mL in DMSO
• Storage: -20°C
• InChI: InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
• InChIKey: PYZRQGJRPPTADH-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N

Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used as an adjunct in treating clinical depression. For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I.

Reference

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