For research use only. Not for therapeutic Use.
Lalistat 2(Cat No.:I044111)is a selective, small-molecule inhibitor of lysosomal acid lipase (LAL), an enzyme responsible for hydrolyzing cholesteryl esters and triglycerides within lysosomes. By blocking LAL activity, Lalistat 2 is widely used in research to model LAL deficiency and study lipid storage disorders such as Wolman disease and cholesterol ester storage disease (CESD). It helps elucidate the role of LAL in intracellular lipid metabolism, autophagy, and inflammation. Lalistat 2 enables detailed analysis of lipid trafficking pathways and supports the development of therapeutic strategies targeting lysosomal lipid dysregulation.
CAS Number | 1234569-09-5 |
Synonyms | (4-piperidin-1-yl-1,2,5-thiadiazol-3-yl) piperidine-1-carboxylate |
Molecular Formula | C13H20N4O2S |
Purity | ≥95% |
IUPAC Name | (4-piperidin-1-yl-1,2,5-thiadiazol-3-yl) piperidine-1-carboxylate |
InChI | InChI=1S/C13H20N4O2S/c18-13(17-9-5-2-6-10-17)19-12-11(14-20-15-12)16-7-3-1-4-8-16/h1-10H2 |
InChIKey | PNYYVHOTXOEBEV-UHFFFAOYSA-N |
SMILES | C1CCN(CC1)C2=NSN=C2OC(=O)N3CCCCC3 |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |