L-Prolinamide

• CAT Number: R046461
• CAS Number: 7531-52-4
• Molecular Formula: C5H10N2O
• Molecular Weight: 114.15
• Purity: ≥95%
• Synonyms: (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-2-Pyrrolidinecarboxamide; (2S)-Pyrrolidine-2-carboxylic Acid Amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide
• Storage: -20°C
• IUPAC Name: (2S)-pyrrolidine-2-carboxamide
• InChI: InChI=1S/C5H10N2O/c6-5(8)4-2-1-3-7-4/h4,7H,1-3H2,(H2,6,8)/t4-/m0/s1
• InChIKey: VLJNHYLEOZPXFW-BYPYZUCNSA-N
• SMILES: C1C[C@H](NC1)C(=O)N

L-Prolinamide（Cat No.:R046461）is the amide derivative of the naturally occurring amino acid L-proline, featuring a five-membered pyrrolidine ring and a terminal carboxamide group instead of the typical carboxylic acid. It retains the (S)-configuration of L-proline, making it chiral and biologically relevant. L-Prolinamide is used as a chiral building block and organocatalyst in asymmetric synthesis, especially in enamine- and iminium-catalyzed reactions. Its cyclic structure imparts conformational rigidity, enhancing stereocontrol in chemical transformations. It is also studied for its potential in medicinal chemistry and peptide modification due to its structural mimicry of proline residues.