L-Homopropargylglycine hydrochloride

• CAT Number: I045294
• CAS Number: 942518-19-6
• Molecular Formula: C6H10ClNO2
• Molecular Weight: 163.60
• Purity: ≥95%
• Synonyms: (2S)-2-aminohex-5-ynoic acid;hydrochloride
• InChI: InChI=1S/C6H9NO2.ClH/c1-2-3-4-5(7)6(8)9;/h1,5H,3-4,7H2,(H,8,9);1H/t5-;/m0./s1
• InChIKey: XGBWOGGSQVMSRX-JEDNCBNOSA-N
• SMILES: C#CCC[C@@H](C(=O)O)N.Cl

L-Homopropargylglycine hydrochloride（Cat No.:I045294）is a non-natural alkyne-containing amino acid used in chemical biology and bioorthogonal labeling. As a methionine analog, it can be incorporated into proteins through metabolic labeling, enabling site-specific conjugation via copper-catalyzed azide–alkyne cycloaddition (CuAAC) “click” chemistry. The hydrochloride salt form improves solubility and handling in aqueous systems. This reagent is valuable for studying protein synthesis, tracking biomolecules in living cells, and creating functionalized proteins for biochemical assays. Its precise reactivity and biocompatibility make it a key tool in proteomics, imaging, and targeted bioconjugation research.