For research use only. Not for therapeutic Use.
Kuwanon H（Cat No.:R072581）is a prenylated flavonoid isolated from the root bark of Morus species (mulberry), known for their medicinal and nutritional value. It demonstrates a wide range of pharmacological activities, including antibacterial, antiviral, anti-inflammatory, antioxidant, and anticancer effects. Mechanistically, Kuwanon H interferes with microbial growth, suppresses inflammatory mediators, and induces apoptosis in tumor cells by modulating pathways such as NF-κB and MAPK. Preclinical studies highlight its potential in treating infectious diseases, inflammatory disorders, and cancers. As a natural bioactive compound, Kuwanon H serves as a promising lead in drug discovery research.
| CAS Number | 76472-87-2 |
| Synonyms | 8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one |
| Molecular Formula | C45H44O11 |
| Purity | ≥95% |
| IUPAC Name | 8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one |
| InChI | InChI=1S/C45H44O11/c1-21(2)6-10-27-33(48)15-14-29(41(27)53)42(54)38-31(26-12-8-24(46)18-34(26)49)16-23(5)17-32(38)39-36(51)20-37(52)40-43(55)30(11-7-22(3)4)44(56-45(39)40)28-13-9-25(47)19-35(28)50/h6-9,12-15,17-20,31-32,38,46-53H,10-11,16H2,1-5H3/t31-,32-,38-/m0/s1 |
| InChIKey | DKBPTKFKCCNXNH-QXGWMLRCSA-N |
| SMILES | CC1=C[C@@H]([C@H]([C@@H](C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C(=C(C=C3)O)CC=C(C)C)O)C4=C(C=C(C5=C4OC(=C(C5=O)CC=C(C)C)C6=C(C=C(C=C6)O)O)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
