Kgp-IN-1 hydrochloride（Cat No.:I014977）is a small-molecule inhibitor targeting lysine-gingipain (Kgp), a cysteine protease secreted by Porphyromonas gingivalis, a key pathogen in periodontal disease. By selectively blocking Kgp activity, this compound disrupts bacterial virulence mechanisms, including hemoglobin degradation, nutrient acquisition, and immune evasion. Kgp-IN-1 hydrochloride is widely applied in oral health and infectious disease research to explore therapeutic strategies against periodontitis and related systemic conditions. Its hydrochloride salt form enhances solubility and stability, making it a reliable tool for biochemical assays, drug discovery, and pathogen-host interaction studies.