KDOAM-25 citrate

• CAT Number: I046108
• CAS Number: 2448475-08-7
• Molecular Formula: C21H33N5O9
• Molecular Weight: 499.51
• Purity: ≥95%
• Synonyms: 2-[[[2-[2-(dimethylamino)ethyl-ethylamino]-2-oxoethyl]amino]methyl]pyridine-4-carboxamide;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChI: InChI=1S/C15H25N5O2.C6H8O7/c1-4-20(8-7-19(2)3)14(21)11-17-10-13-9-12(15(16)22)5-6-18-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-6,9,17H,4,7-8,10-11H2,1-3H3,(H2,16,22);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChIKey: LOVVSPOOXGDJRT-UHFFFAOYSA-N
• SMILES: CCN(CCN(C)C)C(=O)CNCC1=NC=CC(=C1)C(=O)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

KDOAM-25 citrate（Cat No.:I046108）is a selective small-molecule inhibitor of lysine demethylase 5 (KDM5/JARID1) family enzymes, which regulate gene expression through histone H3K4 demethylation. By blocking KDM5 activity, KDOAM-25 modulates chromatin remodeling and epigenetic transcriptional control, providing a powerful tool for studying cancer biology, stem cell regulation, and developmental pathways. The citrate salt enhances solubility and stability, facilitating experimental applications in biochemical assays and cellular models. Widely used in epigenetics and oncology research, this compound is supplied strictly for scientific research use only, not for therapeutic purposes.