Kdo Azide

• CAT Number: I042595
• CAS Number: 1380099-68-2
• Molecular Formula: C8H16N4O7
• Molecular Weight: 280.24
• Purity: ≥95%
• Synonyms: azane;(4R,5R,6R,7R)-8-azido-4,5,6,7-tetrahydroxy-2-oxooctanoic acid
• InChI: InChI=1S/C8H13N3O7.H3N/c9-11-10-2-5(14)7(16)6(15)3(12)1-4(13)8(17)18;/h3,5-7,12,14-16H,1-2H2,(H,17,18);1H3/t3-,5-,6-,7-;/m1./s1
• InChIKey: MMNDMXWELAQOMB-LBDSCFHVSA-N
• SMILES: C(C(C(C(C(CN=[N+]=[N-])O)O)O)O)C(=O)C(=O)O.N

Kdo Azide (Cat No.: I042595) is a bioorthogonal sugar analog used in glycobiology and chemical biology research. It features an azide functional group, enabling selective labeling through click chemistry, particularly for tracking bacterial lipopolysaccharide (LPS) biosynthesis. Kdo is a key component of LPS in Gram-negative bacteria, and the azide-modified version allows visualization or isolation of bacterial cell surface glycans. Kdo Azide is valuable for studying bacterial pathogenesis, cell wall remodeling, and the development of antimicrobial strategies.

Reference

[1]. Fugier E, et al. Rapid and Specific Enrichment of Culturable Gram Negative Bacteria Using Non-Lethal Copper-Free Click Chemistry Coupled with Magnetic Beads Separation. PLoS One. 2015 Jun 10;10(6):e0127700.
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