For research use only. Not for therapeutic Use.
KDM2B-IN-1（Cat No.:I044385）is a potent and selective inhibitor of KDM2B, a JmjC domain-containing histone demethylase that specifically demethylates H3K36me2. By blocking KDM2B activity, this compound modulates epigenetic regulation of gene expression, affecting pathways linked to cell proliferation, differentiation, and tumorigenesis. KDM2B-IN-1 is a valuable research tool for studying the role of histone demethylation in cancer and developmental biology. It exhibits strong cellular permeability and specificity, making it suitable for both in vitro and in vivo studies. Its application supports the advancement of epigenetic-based therapeutic strategies.
| CAS Number | 1965248-33-2 |
| Synonyms | 1-cyclobutyl-4-[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)-4,5-dihydroimidazol-2-yl]piperazine |
| Molecular Formula | C21H30N4O2S |
| Purity | ≥95% |
| IUPAC Name | 1-cyclobutyl-4-[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)-4,5-dihydroimidazol-2-yl]piperazine |
| InChI | InChI=1S/C21H30N4O2S/c26-28(27,20-9-8-17-4-1-2-5-18(17)16-20)25-11-10-22-21(25)24-14-12-23(13-15-24)19-6-3-7-19/h8-9,16,19H,1-7,10-15H2 |
| InChIKey | JPPPBGVARYKPJW-UHFFFAOYSA-N |
| SMILES | C1CCC2=C(C1)C=CC(=C2)S(=O)(=O)N3CCN=C3N4CCN(CC4)C5CCC5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
