For research use only. Not for therapeutic Use.
KD 5170（Cat No.:I011616）is a potent histone deacetylase (HDAC) inhibitor, particularly targeting class I and II HDACs. By blocking HDAC activity, KD 5170 increases histone acetylation, leading to altered gene expression, cell cycle arrest, and induction of apoptosis in cancer cells. It has demonstrated strong antiproliferative effects in various tumor models and is used in cancer research to explore epigenetic regulation of oncogenes and tumor suppressor genes. KD 5170 is a valuable tool for investigating HDAC-mediated transcriptional control and holds potential for the development of epigenetic therapies in oncology.
| CAS Number | 940943-37-3 |
| Synonyms | S-[2-[6-[[4-[3-(dimethylamino)propoxy]phenyl]sulfonylamino]pyridin-3-yl]-2-oxoethyl] ethanethioate |
| Molecular Formula | C20H25N3O5S2 |
| Purity | ≥95% |
| IUPAC Name | S-[2-[6-[[4-[3-(dimethylamino)propoxy]phenyl]sulfonylamino]pyridin-3-yl]-2-oxoethyl] ethanethioate |
| InChI | InChI=1S/C20H25N3O5S2/c1-15(24)29-14-19(25)16-5-10-20(21-13-16)22-30(26,27)18-8-6-17(7-9-18)28-12-4-11-23(2)3/h5-10,13H,4,11-12,14H2,1-3H3,(H,21,22) |
| InChIKey | KXWBUKMWZKTHCV-UHFFFAOYSA-N |
| SMILES | CC(=O)SCC(=O)C1=CN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)OCCCN(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
