For research use only. Not for therapeutic Use.
Kansuinine B（Cat No.:I044343）is a naturally occurring lignan compound derived from Anemarrhena asphodeloides, recognized for its anti-inflammatory and neuroprotective properties. It acts by modulating key inflammatory pathways, including NF-κB and MAPK, thereby reducing the expression of pro-inflammatory cytokines. Kansuinine B also demonstrates antioxidant activity, helping to mitigate oxidative stress in cellular models. Preclinical studies suggest its potential in preventing or slowing the progression of neurodegenerative conditions such as Alzheimer’s disease. Its dual role in inflammation control and oxidative defense highlights Kansuinine B as a promising candidate for therapeutic development.
| CAS Number | 57685-46-8 |
| Synonyms | [(1S,3S,4S,6S,9R,10S,12R,13S,14R,15R,16S)-1,14-diacetyloxy-10-benzoyloxy-9,15,16-trihydroxy-3,7,7,15-tetramethyl-11-methylidene-2,8-dioxo-5-oxatricyclo[11.3.0.04,6]hexadecan-12-yl] benzoate |
| Molecular Formula | C38H42O14 |
| Purity | ≥95% |
| IUPAC Name | [(1S,3S,4S,6S,9R,10S,12R,13S,14R,15R,16S)-1,14-diacetyloxy-10-benzoyloxy-9,15,16-trihydroxy-3,7,7,15-tetramethyl-11-methylidene-2,8-dioxo-5-oxatricyclo[11.3.0.04,6]hexadecan-12-yl] benzoate |
| InChI | InChI=1S/C38H42O14/c1-18-26(50-33(44)22-14-10-8-11-15-22)24-31(48-20(3)39)37(7,47)35(46)38(24,52-21(4)40)29(42)19(2)28-32(49-28)36(5,6)30(43)25(41)27(18)51-34(45)23-16-12-9-13-17-23/h8-17,19,24-28,31-32,35,41,46-47H,1H2,2-7H3/t19-,24-,25+,26-,27-,28-,31+,32+,35-,37-,38+/m0/s1 |
| InChIKey | JFOILMZFESGPDU-GXRLDEOZSA-N |
| SMILES | C[C@H]1[C@H]2[C@@H](O2)C(C(=O)[C@@H]([C@H](C(=C)[C@@H]([C@H]3[C@H]([C@]([C@@H]([C@@]3(C1=O)OC(=O)C)O)(C)O)OC(=O)C)OC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)O)(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
