For research use only. Not for therapeutic Use.
Kansuinine A（Cat No.:I029982）is a bioactive lignan isolated from Anemarrhena asphodeloides, a traditional Chinese medicinal herb. It exhibits potent anti-inflammatory and neuroprotective effects, primarily by inhibiting the NF-κB and MAPK signaling pathways. Kansuinine A has shown promise in reducing oxidative stress, suppressing pro-inflammatory cytokine production, and protecting neurons from damage. Its antioxidant properties make it a candidate for treating neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Ongoing studies are investigating its pharmacological profile and therapeutic potential across various inflammation-related and neurodegenerative disease models.
| CAS Number | 57701-86-7 |
| Synonyms | [(1R,2R,4S,5S,6R,7R,9S,10S,11S,13R,15R)-2,5,7,9,11-pentaacetyloxy-1-hydroxy-4,12,12,15-tetramethyl-8-methylidene-14-oxo-16-oxatricyclo[11.2.1.02,6]hexadecan-10-yl] benzoate |
| Molecular Formula | C37H46O15 |
| Purity | ≥95% |
| IUPAC Name | [(1R,2R,4S,5S,6R,7R,9S,10S,11S,13R,15R)-2,5,7,9,11-pentaacetyloxy-1-hydroxy-4,12,12,15-tetramethyl-8-methylidene-14-oxo-16-oxatricyclo[11.2.1.02,6]hexadecan-10-yl] benzoate |
| InChI | InChI=1S/C37H46O15/c1-17-16-36(51-24(8)42)26(28(17)46-20(4)38)29(47-21(5)39)18(2)30(48-22(6)40)31(50-34(44)25-14-12-11-13-15-25)33(49-23(7)41)35(9,10)32-27(43)19(3)37(36,45)52-32/h11-15,17,19,26,28-33,45H,2,16H2,1,3-10H3/t17-,19+,26+,28-,29-,30-,31+,32-,33+,36+,37+/m0/s1 |
| InChIKey | VKHCUWUNVKZFBM-PNKWBUBPSA-N |
| SMILES | C[C@H]1C[C@]2([C@H]([C@H]1OC(=O)C)[C@H](C(=C)[C@@H]([C@H]([C@H](C([C@@H]3C(=O)[C@H]([C@]2(O3)O)C)(C)C)OC(=O)C)OC(=O)C4=CC=CC=C4)OC(=O)C)OC(=O)C)OC(=O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
