JNJ-40418677

For research use only. Not for therapeutic Use.

  • CAT Number: R067040
  • CAS Number: 1146594-87-7
  • Molecular Formula: C26H22F6O2
  • Molecular Weight: 480.44
  • Purity: ≥95%
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JNJ-40418677(Cat No.:R067040)is an investigational small molecule being developed by Janssen Pharmaceuticals, designed as a selective inhibitor of the TYK2 (Tyrosine Kinase 2) enzyme. TYK2 is involved in the signaling of several key cytokines that regulate immune responses, including those associated with autoimmune diseases. By inhibiting TYK2, JNJ-40418677 aims to modulate the immune system, offering potential therapeutic benefits in conditions such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease. The compound is being studied in clinical trials to assess its safety, efficacy, and ability to manage chronic inflammatory conditions.


CAS Number 1146594-87-7
Synonyms

(2S)-2-[3,5-bis[4-(trifluoromethyl)phenyl]phenyl]-4-methylpentanoic acid

Molecular Formula C26H22F6O2
Purity ≥95%
IUPAC Name (2S)-2-[3,5-bis[4-(trifluoromethyl)phenyl]phenyl]-4-methylpentanoic acid
InChI InChI=1S/C26H22F6O2/c1-15(2)11-23(24(33)34)20-13-18(16-3-7-21(8-4-16)25(27,28)29)12-19(14-20)17-5-9-22(10-6-17)26(30,31)32/h3-10,12-15,23H,11H2,1-2H3,(H,33,34)/t23-/m0/s1
InChIKey RQOWDDLKGBMJFX-QHCPKHFHSA-N
SMILES CC(C)C[C@@H](C1=CC(=CC(=C1)C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C=C3)C(F)(F)F)C(=O)O
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