For research use only. Not for therapeutic Use.
Janelia Fluor® 646, Tetrazine（Cat No.:I044580）is a bright, far-red fluorescent dye conjugated to a tetrazine moiety, designed for rapid and specific bioorthogonal labeling via inverse electron-demand Diels–Alder (IEDDA) reactions. With excellent photostability, high quantum yield, and minimal background fluorescence, it enables high-resolution live-cell and fixed-cell imaging. The tetrazine group reacts efficiently with trans-cyclooctene (TCO)- or strained alkene-tagged biomolecules, making it ideal for click chemistry applications in cellular and molecular biology. Janelia Fluor® 646, Tetrazine is especially valuable for super-resolution microscopy and dynamic tracking of biomolecular processes.
| CAS Number | 2042192-00-5 |
| Synonyms | 2-[3-(azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethylbenzo[b][1]benzosilin-10-yl]-4-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methylcarbamoyl]benzoate |
| Molecular Formula | C38H35N7O3Si |
| Purity | ≥95% |
| IUPAC Name | 2-[3-(azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethylbenzo[b][1]benzosilin-10-yl]-4-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methylcarbamoyl]benzoate |
| InChI | InChI=1S/C38H35N7O3Si/c1-49(2)33-20-27(44-15-3-16-44)10-13-30(33)35(31-14-11-28(21-34(31)49)45-17-4-18-45)32-19-26(9-12-29(32)38(47)48)37(46)39-22-24-5-7-25(8-6-24)36-42-40-23-41-43-36/h5-14,19-21,23H,3-4,15-18,22H2,1-2H3,(H-,39,46,47,48) |
| InChIKey | CPWVRCGDSYQFSV-UHFFFAOYSA-N |
| SMILES | C[Si]1(C2=CC(=[N+]3CCC3)C=CC2=C(C4=C1C=C(C=C4)N5CCC5)C6=C(C=CC(=C6)C(=O)NCC7=CC=C(C=C7)C8=NN=CN=N8)C(=O)[O-])C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
