For research use only. Not for therapeutic Use.
Janelia Fluor® 646, Maleimide（Cat No.:I045769）is a far-red fluorescent dye engineered with a maleimide reactive group for selective labeling of thiol groups on cysteine residues in proteins and peptides. With excitation and emission maxima near 646/664 nm, it provides exceptional brightness, low background, and photostability, making it highly suited for confocal microscopy, flow cytometry, and super-resolution imaging. Its far-red fluorescence reduces cellular autofluorescence and supports multiplexing with other dyes. Janelia Fluor® 646, Maleimide is widely used for live-cell imaging, protein tracking, and advanced fluorescence-based biological research applications.
| Synonyms | 2-[3-(azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethylbenzo[b][1]benzosilin-10-yl]-4-[2-(2,5-dioxopyrrol-1-yl)ethylcarbamoyl]benzoate |
| Molecular Formula | C35H34N4O5Si |
| Purity | ≥95% |
| IUPAC Name | 2-[3-(azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethylbenzo[b][1]benzosilin-10-yl]-4-[2-(2,5-dioxopyrrol-1-yl)ethylcarbamoyl]benzoate |
| InChI | InChI=1S/C35H34N4O5Si/c1-45(2)29-20-23(37-14-3-15-37)6-9-26(29)33(27-10-7-24(21-30(27)45)38-16-4-17-38)28-19-22(5-8-25(28)35(43)44)34(42)36-13-18-39-31(40)11-12-32(39)41/h5-12,19-21H,3-4,13-18H2,1-2H3,(H-,36,42,43,44) |
| InChIKey | AZBDLOPMXNNQQB-UHFFFAOYSA-N |
| SMILES | C[Si]1(C2=CC(=[N+]3CCC3)C=CC2=C(C4=C1C=C(C=C4)N5CCC5)C6=C(C=CC(=C6)C(=O)NCCN7C(=O)C=CC7=O)C(=O)[O-])C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
