For research use only. Not for therapeutic Use.
J-2156 TFA（Cat No.:I015384）is a selective and potent agonist of the δ-opioid receptor (DOR), supplied as its trifluoroacetate salt. It exhibits high receptor affinity and efficacy, making it a valuable tool for studying opioid receptor signaling, pain modulation, and neuroprotection. Unlike μ-opioid receptor agonists, J-2156 demonstrates reduced risk of dependence, allowing researchers to explore novel analgesic pathways with improved safety profiles. It is widely applied in neurobiology and pharmacology studies to investigate mood regulation, antidepressant mechanisms, and therapeutic potential in pain and neurological disorders.
| CAS Number | 2387505-73-7 |
| Synonyms | (2S)-4-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanamide;2,2,2-trifluoroacetic acid |
| Molecular Formula | C26H29F3N4O6S |
| Purity | ≥95% |
| IUPAC Name | (2S)-4-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanamide;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C24H28N4O4S.C2HF3O2/c1-16-11-12-22(19-10-6-5-9-18(16)19)33(31,32)28-20(13-14-25)24(30)27-21(23(26)29)15-17-7-3-2-4-8-17;3-2(4,5)1(6)7/h2-12,20-21,28H,13-15,25H2,1H3,(H2,26,29)(H,27,30);(H,6,7)/t20-,21-;/m0./s1 |
| InChIKey | OCEMIQKESMKGAP-GUTACTQSSA-N |
| SMILES | CC1=CC=C(C2=CC=CC=C12)S(=O)(=O)N[C@@H](CCN)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N.C(=O)(C(F)(F)F)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
