For research use only. Not for therapeutic Use.
Isotetrandrine（Cat No.:R035202）is a bisbenzylisoquinoline alkaloid primarily isolated from plants of the Stephania genus. Known for its diverse pharmacological activities, it has been studied for anti-inflammatory, immunomodulatory, and anticancer effects. Research suggests isotetrandrine can inhibit NF-κB activation, suppress pro-inflammatory cytokines, and induce apoptosis in cancer cell models. Additionally, it exhibits potential cardiovascular and neuroprotective properties by modulating calcium channels and reducing oxidative stress. Its broad biological profile makes isotetrandrine a valuable compound for studies in inflammation, oncology, cardiovascular health, and neurological disease research.
| CAS Number | 477-57-6 |
| Synonyms | (1S,14R)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene |
| Molecular Formula | C38H42N2O6 |
| Purity | ≥95% |
| IUPAC Name | (1S,14R)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene |
| InChI | InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30+/m0/s1 |
| InChIKey | WVTKBKWTSCPRNU-XZWHSSHBSA-N |
| SMILES | CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
