Isopropyl Methanesulfonate

• CAT Number: R024506
• CAS Number: 926-06-7
• Molecular Formula: C4H10O3S
• Molecular Weight: 138.18
• Purity: ≥95%
• Synonyms: 2-Propyl Methanesulfonate; Isopropyl Mesylate; Isopropyl Methanesulfonate; Isopropyl Methanesulphonate; Methanesulfonic Acid, 1-Methylethyl Ester; Methanesulfonic Acid, Isopropyl Ester
• Storage: -20°C
• IUPAC Name: propan-2-yl methanesulfonate
• InChI: InChI=1S/C4H10O3S/c1-4(2)7-8(3,5)6/h4H,1-3H3
• InChIKey: SWWHCQCMVCPLEQ-UHFFFAOYSA-N
• SMILES: CC(C)OS(=O)(=O)C

Isopropyl methanesulfonate(CAT: R024506) is an alkyl sulfonate ester consisting of an isopropyl group bonded to a methanesulfonate (mesylate) moiety. This compound functions as a potent alkylating agent in organic synthesis, where it is used to introduce isopropyl groups through nucleophilic substitution reactions. Its mesylate leaving group is highly reactive, making it suitable for converting alcohols and amines into isopropylated derivatives under mild conditions. Due to its electrophilic nature, isopropyl methanesulfonate is also studied for its mutagenic and genotoxic properties and is subject to regulation in pharmaceutical manufacturing.