Isopropyl diethyl malonate

• CAT Number: R070667
• CAS Number: 759-36-4
• Molecular Formula: C10H18O4
• Molecular Weight: 202.25
• Purity: ≥95%
• Synonyms: Isopropyl malonic acid diethyl ester
• Storage: RT
• IUPAC Name: diethyl 2-propan-2-ylpropanedioate
• InChI: InChI=1S/C10H18O4/c1-5-13-9(11)8(7(3)4)10(12)14-6-2/h7-8H,5-6H2,1-4H3
• InChIKey: BYQFBFWERHXONI-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(C(C)C)C(=O)OCC

Isopropyl diethyl malonate(CAT: R070667) is an ester derivative of malonic acid featuring one isopropyl group and two ethyl ester functionalities. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its structure allows for nucleophilic substitution at the methylene carbon between the ester groups, making it ideal for alkylation, condensation, and decarboxylation reactions. Isopropyl diethyl malonate is often used to construct substituted acetic acids, barbiturates, and heterocyclic compounds.