Isoniazid-d4 is a deuterated form of isoniazid, an antibiotic used primarily for the treatment and prevention of tuberculosis. The “d4” designation indicates the replacement of four hydrogen atoms with deuterium. This deuterated analog is used as a stable isotope-labeled internal standard in mass spectrometry and other analytical techniques. Isoniazid functions by inhibiting the synthesis of mycolic acids in the bacterial cell wall, crucial for Mycobacterium tuberculosis. Isoniazid-d4 is employed in pharmacokinetic studies and drug monitoring to accurately measure isoniazid levels and assess its metabolism and efficacy in clinical research.
| Catalog Number | R007266 |
| CAS Number | 774596-24-6 |
| Synonyms | 4-(Pyridine-d4)carboxylic Acid Hydrazide; Isonicotinic Acid-d4 Hydrazide; 4-(Hydrazinocarbonyl)pyridine-d4; 4-(Pyridine-d4)carbonylhydrazine; 4-(Pyridine-d4)carboxylic Hydrazide; 4-(Pyridyl-d4)carbonylhydrazide; 5015 R.P.-d4; Armazid-d4; Armazide-d4; |
| Molecular Formula | C6H7N3O |
| Purity | 95% |
| Storage | -20°C |
| IUPAC Name | 2,3,5,6-tetradeuteriopyridine-4-carbohydrazide |
| InChI | InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)/i1D,2D,3D,4D |
| InChIKey | QRXWMOHMRWLFEY-RHQRLBAQSA-N |
| SMILES | [2H]C1=C(N=C(C(=C1C(=O)NN)[2H])[2H])[2H] |
