Isofagomine D-Tartrate

• CAT Number: R009129
• CAS Number: 957230-65-8
• Molecular Formula: C6H13NO3 • C4H6O6
• Molecular Weight: 297.30
• Purity: ≥95%
• Synonyms: (3R,4R,5R)-5-(Hydroxymethyl)-3,4-piperidinediol ?(2S,3S)-2,3-Dihydroxybutanedioate
• Target: Glucosidase
• Storage: -20°C
• IUPAC Name: (2S,3S)-2,3-dihydroxybutanedioic acid;(3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol
• InChI: InChI=1S/C6H13NO3.C4H6O6/c8-3-4-1-7-2-5(9)6(4)10;5-1(3(7)8)2(6)4(9)10/h4-10H,1-3H2;1-2,5-6H,(H,7,8)(H,9,10)/t4-,5-,6-;1-,2-/m10/s1
• InChIKey: ULBPPCHRAVUQMC-AWUBODBRSA-N
• SMILES: C1[C@@H]([C@H]([C@@H](CN1)O)O)CO.[C@H]([C@@H](C(=O)O)O)(C(=O)O)O

Isofagomine D-tartrate（Cat No.:R009129）is the tartrate salt form of isofagomine, a potent pharmacological chaperone and competitive inhibitor of β-glucosidase enzymes, including glucocerebrosidase. It is primarily studied for its potential therapeutic role in treating Gaucher disease and other lysosomal storage disorders by stabilizing misfolded enzymes and enhancing their trafficking to lysosomes. The D-tartrate counterion improves solubility and formulation properties for oral delivery. Isofagomine D-tartrate is typically supplied as a crystalline solid, soluble in water, and used in biochemical, pharmacological, and clinical research related to enzyme replacement and chaperone therapies.