For research use only. Not for therapeutic Use.
Isatuximab(Cat No.:I044209)is a humanized IgG1 monoclonal antibody that targets CD38, a surface glycoprotein highly expressed on multiple myeloma cells. By binding to CD38, isatuximab induces cancer cell death through multiple mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and direct apoptosis. It also modulates the immune microenvironment by reducing immunosuppressive cells. Approved for use in combination therapies for relapsed or refractory multiple myeloma, isatuximab offers a potent, targeted treatment option that enhances response rates and prolongs progression-free survival in patients with advanced disease.
CAS Number | 1461640-62-9 |
Purity | ≥95% |
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