For research use only. Not for therapeutic Use.
IONIS-FB-LRx sodium(CAT: I040322) is a ligand-conjugated antisense oligonucleotide (ASO) specifically designed to target and suppress the expression of complement factor B (CFB), a key component of the alternative complement pathway. By reducing circulating CFB levels, IONIS-FB-LRx modulates immune-mediated inflammation implicated in retinal degenerative disorders. It holds particular promise for geographic atrophy (GA) research, a late-stage form of dry age-related macular degeneration (AMD). Engineered for enhanced liver uptake and stability, the sodium form supports systemic delivery and therapeutic exploration. IONIS-FB-LRx sodium is a valuable tool in complement biology and retinal disease research.
| Purity | ≥95% |
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