For research use only. Not for therapeutic Use.
Iodoacetyl-LC-biotin（Cat No.:R003017）is a thiol-reactive biotinylation reagent designed for selective labeling of cysteine residues in proteins and peptides. It features an iodoacetyl group that forms stable thioether bonds with sulfhydryl groups, and a biotin moiety for strong, specific binding to streptavidin or avidin systems. The long-chain (LC) spacer arm provides reduced steric hindrance, improving accessibility and interaction efficiency in detection or purification assays. Widely used in proteomics, pull-down assays, and affinity labeling, Iodoacetyl-LC-biotin enables sensitive and site-specific tagging for biochemical and diagnostic applications.
| CAS Number | 93285-75-7 |
| Synonyms | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[6-[(2-iodoacetyl)amino]hexyl]pentanamide |
| Molecular Formula | C18H31IN4O3S |
| Purity | ≥95% |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[6-[(2-iodoacetyl)amino]hexyl]pentanamide |
| InChI | InChI=1S/C18H31IN4O3S/c19-11-16(25)21-10-6-2-1-5-9-20-15(24)8-4-3-7-14-17-13(12-27-14)22-18(26)23-17/h13-14,17H,1-12H2,(H,20,24)(H,21,25)(H2,22,23,26)/t13-,14-,17-/m0/s1 |
| InChIKey | DNXDWMHPTVQBIP-ZQIUZPCESA-N |
| SMILES | C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCCCCCNC(=O)CI)NC(=O)N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
