Iodoacetamide-PEG5-azide

• CAT Number: I044550
• Molecular Formula: C14H27IN4O6
• Molecular Weight: 474.29
• Purity: ≥95%
• Synonyms: N-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-2-iodoacetamide
• InChI: InChI=1S/C14H27IN4O6/c15-13-14(20)17-1-3-21-5-7-23-9-11-25-12-10-24-8-6-22-4-2-18-19-16/h1-13H2,(H,17,20)
• InChIKey: RVCJJFODINCSQX-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCOCCOCCN=[N+]=[N-])NC(=O)CI

Iodoacetamide-PEG5-azide（Cat No.:I044550）is a bifunctional crosslinker combining an iodoacetamide group and an azide moiety connected via a PEG5 spacer. The iodoacetamide group selectively reacts with thiol groups on cysteine residues, enabling site-specific protein or peptide labeling. The azide group allows bioorthogonal conjugation through click chemistry, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). The PEG5 linker enhances solubility and provides spatial flexibility, reducing steric hindrance in complex biological environments. Iodoacetamide-PEG5-azide is ideal for bioconjugation, proteomics, and the development of multifunctional biomolecules in drug delivery and diagnostic research.