Indole-C2-amide-C2-NH2

• CAT Number: I042491
• CAS Number: 215789-29-0
• Molecular Formula: C13H17N3O
• Molecular Weight: 231.29
• Purity: ≥95%
• Synonyms: 3-amino-N-[2-(1H-indol-3-yl)ethyl]propanamide
• InChI: InChI=1S/C13H17N3O/c14-7-5-13(17)15-8-6-10-9-16-12-4-2-1-3-11(10)12/h1-4,9,16H,5-8,14H2,(H,15,17)
• InChIKey: ANPPXRSQOVOACQ-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=CN2)CCNC(=O)CCN

Indole-C2-amide-C2-NH₂( Cat No.: I042491) is a synthetic small molecule featuring an indole core with a two-carbon linker terminating in an amide group and a primary amine. This structure mimics natural bioactive motifs found in tryptophan-derived compounds and can interact with various biological targets, including receptors and enzymes. Its modular design makes it a useful scaffold in medicinal chemistry for drug development, particularly in targeting neurological, oncological, or inflammatory pathways. Indole-C2-amide-C2-NH₂ is commonly used in structure–activity relationship (SAR) studies and molecular probe development.

Reference

[1]. Murugan RN, et al. Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. Bioorg Med Chem. 2013 May 1;21(9):2623-34.