Indole-5-carboxylic Acid

• CAT Number: R019613
• CAS Number: 1670-81-1
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.16
• Purity: ≥95%
• Synonyms: 5-Carboxyindole
• Storage: -20°C
• IUPAC Name: 1H-indole-5-carboxylic acid
• InChI: InChI=1S/C9H7NO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,(H,11,12)
• InChIKey: IENZCGNHSIMFJE-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C=CN2)C=C1C(=O)O

Indole-5-carboxylic acid（Cat No.:R019613）is a heteroaromatic compound featuring a carboxyl group at the 5-position of the indole ring. This structure combines the bioactive indole core—common in natural products and pharmaceuticals—with a functional handle for further derivatization. It serves as a versatile intermediate in the synthesis of drugs, agrochemicals, and fluorescent probes. Its carboxylic acid moiety allows for amide or ester formation, making it useful in building peptide mimetics and kinase inhibitors. Indole-5-carboxylic acid is frequently employed in medicinal chemistry for designing biologically active small molecules.