Indole-2-carboxylic Acid

• CAT Number: R000139
• CAS Number: 1477-50-5
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.16
• Purity: ≥95%
• Synonyms: 2-Carboxyindole; 2-Indolylformic Acid; NSC 16598
• Target: Neuronal Signaling
• Storage: -20°C
• IUPAC Name: 1H-indole-2-carboxylic acid
• InChI: InChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12)
• InChIKey: HCUARRIEZVDMPT-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C=C(N2)C(=O)O

Indole-2-carboxylic acid（Cat No.:R000139）is a heteroaromatic compound featuring a carboxylic acid group at the 2-position of the indole ring. This molecule serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and natural product analogs. Its indole core is a privileged structure in medicinal chemistry, known for its bioactivity and receptor-binding capabilities. The 2-carboxylic acid functionality allows for versatile chemical transformations, including amide coupling and esterification. It is typically supplied as a crystalline solid, sparingly soluble in water, and readily soluble in polar organic solvents.