Indazole-3-carboxylic Acid

• CAT Number: R010283
• CAS Number: 4498-67-3
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.15
• Purity: ≥95%
• Synonyms: 1H-Indazole-3-carboxylic Acid; 3(1H)-Indazolecarboxylic Acid; 3-Carboxy-1H-indazole; 3-Carboxyindazole; NSC 520610;?
• Storage: -20°C
• IUPAC Name: 1H-indazole-3-carboxylic acid
• InChI: InChI=1S/C8H6N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)(H,11,12)
• InChIKey: BHXVYTQDWMQVBI-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=NN2)C(=O)O

Indazole-3-carboxylic acid（Cat No.:R010283）is a heterocyclic aromatic compound featuring a fused benzene-pyrazole ring system with a carboxylic acid group at the 3-position. It serves as a valuable intermediate in pharmaceutical and agrochemical research, particularly for the development of kinase inhibitors, anti-inflammatory agents, and other bioactive molecules. The indazole core contributes to metabolic stability and receptor binding, while the carboxylic acid allows for easy derivatization through amidation or esterification. Typically supplied as a crystalline solid, it is sparingly soluble in water but readily soluble in polar organic solvents.