iMDK quarterhydrate

• CAT Number: I045635
• Molecular Formula: C21H13FN2O2S.1/4H2O
• Molecular Weight: 380.91
• Purity: ≥95%

iMDK quarterhydrate (Cat No.: I045635) is a small-molecule inhibitor of midkine (MDK), a heparin-binding growth factor implicated in cancer progression, angiogenesis, and inflammation. By blocking MDK activity, iMDK suppresses tumor growth and survival signaling, making it a valuable research compound in oncology studies. The quarterhydrate form ensures improved stability and handling for laboratory applications. Researchers use iMDK to explore MDK-driven pathways in cancer, cardiovascular disease, and neuroinflammation. While not approved for therapeutic use, it remains an important probe in disease mechanism and drug discovery research.

Reference

[1]. Naomasa Ishida, et al. A novel PI3K inhibitor iMDK suppresses non-small cell lung Cancer cooperatively with A MEK inhibitor. Exp Cell Res. 2015 Jul 15;335(2):197-206.
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