Imalumab

• CAT Number: I042526
• CAS Number: 1430205-07-4
• Purity: ≥95%

Imalumab (Cat No.:I042526 ) is a human monoclonal antibody that targets oxidized macrophage migration inhibitory factor (oxMIF), a disease-associated isoform of MIF involved in inflammation and tumor progression. By selectively binding to oxMIF, imalumab modulates immune responses and inhibits pro-inflammatory and pro-tumorigenic signaling. It has been investigated in clinical trials for various cancers, including colorectal and non-small cell lung cancer. Imalumab represents a novel immunotherapeutic approach aimed at selectively neutralizing pathogenic MIF activity without affecting its normal physiological functions.

Reference

[1]. Bax HJ, et al. Therapeutic targets and new directions for antibodies developed for ovarian cancer. MAbs. 2016 Nov/Dec;8(8):1437-1455.
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