For research use only. Not for therapeutic Use.
IL-4-inhibitor-1（Cat No.:I029223）is a selective small-molecule compound designed to inhibit interleukin-4 (IL-4) signaling, a key driver of Th2-mediated immune responses involved in allergic inflammation and autoimmune disorders. By blocking IL-4 or its interaction with the IL-4 receptor (IL-4Rα), this inhibitor suppresses downstream JAK-STAT6 pathway activation, reducing the expression of pro-inflammatory cytokines and IgE production. IL-4-inhibitor-1 is valuable in research focused on asthma, atopic dermatitis, and other IL-4-driven diseases. It supports the development of targeted therapies aimed at modulating immune responses and restoring balance in hypersensitive or inflammatory conditions.
| CAS Number | 1332184-63-0 |
| Synonyms | 2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)pyridine-3-carbonitrile |
| Molecular Formula | C18H12FN3O2 |
| Purity | ≥95% |
| IUPAC Name | 2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)pyridine-3-carbonitrile |
| InChI | InChI=1S/C18H12FN3O2/c19-12-4-1-10(2-5-12)15-8-13(14(9-20)18(21)22-15)11-3-6-16(23)17(24)7-11/h1-8,23-24H,(H2,21,22) |
| InChIKey | DWZPPBGRCDPFSS-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=NC(=C(C(=C2)C3=CC(=C(C=C3)O)O)C#N)N)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
