For research use only. Not for therapeutic Use.
IL-17A modulator-19（Cat No.:I045133）is a small-molecule compound designed to selectively modulate the activity of interleukin-17A (IL-17A), a pro-inflammatory cytokine implicated in autoimmune and inflammatory disorders such as psoriasis, rheumatoid arthritis, and ankylosing spondylitis. By inhibiting IL-17A signaling, this modulator suppresses downstream inflammatory pathways, including the production of IL-6 and TNF-α. Unlike biologics that neutralize IL-17A extracellularly, IL-17A modulator-1 may act intracellularly, offering oral bioavailability and dosing flexibility. Supplied for research in cytokine signaling, autoimmune disease mechanisms, and small-molecule immunomodulator development.
| CAS Number | 2748749-29-1 |
| Synonyms | N-[(2S)-1-[4-(3,5-dimethoxypyridin-4-yl)anilino]-1-oxo-3,3-diphenylpropan-2-yl]-2-methylpyrazole-3-carboxamide |
| Molecular Formula | C33H31N5O4 |
| Purity | ≥95% |
| IUPAC Name | N-[(2S)-1-[4-(3,5-dimethoxypyridin-4-yl)anilino]-1-oxo-3,3-diphenylpropan-2-yl]-2-methylpyrazole-3-carboxamide |
| InChI | InChI=1S/C33H31N5O4/c1-38-26(18-19-35-38)32(39)37-31(29(22-10-6-4-7-11-22)23-12-8-5-9-13-23)33(40)36-25-16-14-24(15-17-25)30-27(41-2)20-34-21-28(30)42-3/h4-21,29,31H,1-3H3,(H,36,40)(H,37,39)/t31-/m0/s1 |
| InChIKey | CIIPUPSMHRZVPV-HKBQPEDESA-N |
| SMILES | CN1C(=CC=N1)C(=O)N[C@@H](C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)C5=C(C=NC=C5OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
